THE NATIONAL OLIVE OIL OF ISRAEL

Israeli Bio Tech and Medical Manufacturers Listing Alphabetically

Manufacturer of medical components, devices, specializing in plastic injection molding services and technical design. Products include disposable pumps, drug delivery devices, stopcocks, flow valves.

Algae-derived products for nutraceutical and cosmetics industry. Astaxanthin, a red pigment carotenoid found in algae and aquatic animals that functions as an antioxidant (free-radical scavenger). Feed additive to impart coloration to salmon and trout.

Site-specific stents and stent delivery systems with applications in the urinary, gastrointestinal and respiratory tract for use in malignant and benign obstructions. Biliary stent. Prostatic stent. Ureteral stent.

Molecular tools for the neuroscience community. Molecular tools for calcium, sodium and potassium channels, channel blockers, modulators, antibodies. Inhibitors for PKC, protein phosphatase, tyrosine kinase. Antibodies and toxins.

Analytical and microbiological tests for the pharmaceutical, cosmetics, food, chemical, biological, environmental and agricultural industries.

Aposense for PET, SPECT and MRI based clinical molecular imaging of apoptosis. Therapies based on the targeting of therapeutic agents to apoptosis inflicted tissues.

Cytogenetics, automated spectral karyotyping, FISH probes and imaging. SKY displays chromosomes in unique colors, identifies chromosomal aberrations indicative of cancer, birth defects and genetic problems. Meta scan for Metaphase spreads.

Targeted therapy based on the identification of genes that are highly expressed only in tumors. The regulatory sequences of these genes (e.g. H19) are used to express a toxin gene exclusively within tumor cells, enabling targeted tumor-cell destruction.

Drugs to treat inflammatory diseases and cancer by targeting immune and tumor cell migration, via chemokines. BKT104 targeting production of TNF-Alfa. BKT140, a CXCR4 chemokine receptor antagonist for treatment of tumor growth and metastasis.

Drug development company. Development of novel compounds for the treatment of neurological disorders including schizophrenia, neurodegenerative disease and cancer.

Animal cell culture products, serum-free media and serum substitutes, human cytogenetics products. Distributor of imported chemicals, biochemicals and molecular biology products.

Manufacturer and distributor of disposable medical devices for critical and intensive care units in Israel. Catheter sets, blood pressure kits, intravenous administration lines, angiography introducers, guide wires, ophthalmic drapes.

Development of universal multi-season / multi-strain, intranasal flu vaccine. Technology utilizes a combination of conserved epitopes derived from the influenza virus possessing strong immunogenic capabilities.

Turnkey design and construction of pharmaceutical and biotechnological (API) plants. HVAC and clean rooms, sterile and aseptic filling and packaging lines, Cleaning-in-place and sterilization-in-place (CIP/SIP). Systems comply with USP and EU standards.

EpiClose disposable device for closure of arterial access sites following cardiac catheterization procedures. Quick deployment based on inflation/deflation of balloon that accelerates hemostasis.

Lightweight special garments for the prevention of Deep Vein Thrombosis, treatment of vascular conditions, leg ulcers, venous insufficiency, lymphedema. Intermittent pneumatic compression products powered by energy generated from the patient’s body.

Active Pharmaceutical Ingredients (APIs) and Finished Dosage Forms (FDF) for branded and generic pharmaceutical industries. Sample products: Non-steroidal aromatase inhibitor, CNS depressant, anesthetic, sleeping aid, anti-neoplastic, alkylating agent.

Selective Cargo Delivery (SCD) of therapeutic agents in nano-particles. Suitable for peptides and proteins (e.g. insulin, PTH, GLP-1, erythropoietin, G-CSF, monoclonal antibodies) and non-protein drugs (e.g. heparin, alendronate).

Tempostatin: Selective inhibitor of stromal cell activation, cell migration and excessive collagen type I synthesis in extra-cellular matrix. Applications examined: suppression of fibrosis and uncontrolled activation of tissue repair in heart disease.

Monitoring of vaginal secretions on panty-liners. Self-test of Bacterial Vaginosis and Trichomoniasis. VS-Sense swab tests for abnormal vaginal discharge. Self monitoring of amniotic fluid leakage during pregnancy.

Recombinant cytokine and anti cytokine products and ELISA kits. Product lines include human, murine and rat growth factors and cytokines, Neurotrophins, monoclonal and biotinylated polyclonal antibodies.

Manufacture of prescription, generic and over the counter (OTC) pharmaceutical products. Analgesic, anti-inflammatory, antibiotic, antihistamine, anti-hypertensive, antidepressant, diuretic drugs. Multi-vitamin supplements. Oral contraceptive.

UV transilluminators, gel imaging systems.

Neowater, water-based nanotechnology that mimics intracellular water. Used for oral, topical, ophthalmic, inhaled, transdermal and transmucosal drug delivery. PCR enhancer, transfection enhancer, ligation enhancer, ELISA enhancer, microarray enhancer.

Medical diagnostics system for testing body fluids and cells utilizing a flow cytometer (FC). Kits for analysis of semen, IVF success prediction, hormone levels, genital infections, and immuno-infertility.

Manufacturing of injection-molded plastic disposable medical devices for OEM use in critical care unit, I.V. sets, cardiovascular therapy and hemodialysis bloodline sets. Product lines include stopcocks, manifolds and needleless injection systems.

In silico drug discovery platform based on proprietary 3D computational chemistry technologies specializing on G-protein coupled receptors (GPCRs) to identify novel drug-like compounds that bind specifically to GPCR targets in affinity assays.

Device that enables blood aspiration from infants and retransfusion of red cells back to infants while the plasma is sent to the lab. Isolation of Platelet Rich Plasma (PRP) and retransfusion of activated PRP to enhance healing of tissues.

Biologically active, natural products isolated from microorganisms. Products include A23187, actinomycin D, aflatoxin, anisomycin, cytochalasin, mycotoxins, inhibitors of protein kinases A, C, G, antibiotics, immunosuppressive agents, staurosporine.

Ophthalmic, dermatological and skin-care preparations: Genesis Minerals sunscreens, shampoos, body lotions, Anti Acne Package, antiseptic wet tissues, Kamil Blue - Baby Skin Care products.

Foamix Foam and OILGEL platforms for topical dermatological drugs and cosmetics. DermaFoamix alcohol-free foam as a carrier for corticosteroids, anti-bacterial, anti-fungal, anti-viral drugs, local anesthetics, Anti-allergic agents, vitamins, sunscreen.

Manufacturer of citric acid, citrates, food phosphate salts and various food ingredients.

Manufacturer of crystalline fructose, cornstarch, glucose syrups and a range of modified and instant starches for the food industry. Industrial starches for the paper, corrugated board, plasterboard and textile industries.

CryoHit cryo-therapy platform for treatment of liver, lung and bone cancer. FDA clearance for cancerous and benign conditions including thoracic surgery, gynecology, oncology and urology applications. Integrates with MRI for safety and efficacy.

Biomarkers for autoimmune diseases using glycan molecules as probes via proprietary GlycoChip technology. IBD differential diagnosis (Chron’s disease vs. Ulcerative colitis). Multiple sclerosis assay.

Hermetic Docking Head (HDH) vascular device, for suture-less open and laparoscopic surgical procedures that significantly enhance treatment of aortic and peripheral aneurysms, arterial occlusions and blood vessel traumas.

Topical drugs for healing acute and chronic wounds including diabetic foot ulcer, venous leg ulcer, pressure ulcers. Protein kinase C (PKC) modulating agents that promote formation of new epidermis over wound gap and accelerate matrix remodeling.

Manufacturer of nutraceuticals and food supplements. Products include: Prostacal alleviates symptoms of benign prostatic hyperplasia. FluVir an anti-influenza syrup.

Manufacturer and marketer of prepared media and microbiological diagnostic kits. Systems for the transport and storage of microorganisms, including salmonella, shigella, campylobacter, vibrio spp, pneumococci and anaerobic microorganisms.

Manufacturer of proprietary drugs-of-abuse forensic testing products. Drug-lab quality identification field kits (substance only) for the detection of marijuana, hashish, ecstasy, cocaine, crack and heroin. Suitable for use by police field units.

Drug development focused on DNA repair, cell necrosis and inflammatory pathways associated with tissue injury. PARP inhibitors that block nuclear DNA repair enzyme poly (ADP-ribose) polymerase (PARP). Inhibitor of nitric oxide synthase (iNOS/ NOS II).

Biogenerics, recombinant human proteins. Human Interferon alpha and beta, G-CSF (Filgrastim), GM-CSF (Molgramostim), Erythropoietin (EPO), Follicle Stimulating Hormone (FSH). Heparanase, anti-heparanase mAbs. Small molecule drug development.

Biopharmaceuticals. Specialty plasma derivatives, specific and general immune globulins produced using proprietary chromatographic separation and purification methods. Anticoagulant heparin and antagonist. Parenteral electrolyte solutions.

Microencapsulated vitamins and minerals for dietary supplements, breakfast cereals, dairy foods. Lyc-O-Mato tomato lycopene complex. Beta carotene and carotenoid dispersions. Food and beverage colorant in a variety of red shades. Tomat-o-Red oleoresin.

Natural products based on the carotenoid antioxidant Lycopene extracted from tomatoes.

Manufacturer of powdered food products for human consumption, pet foods and veterinary milk substitutes.

Materna baby food and milk products.

Biological testing of medical products, cosmetics, water, food and beverages for bacteria, fungi and yeast count, classification and identification.

Expandable Fixion Intramedullary Nailing Systems for fracture fixation. Expandable B-Twin Spinal System for use in lumbar spinal fusion. Quantum carbon fiber reinforced composite material for the treatment of fractures of the long bones.

Painless microneedle devices for drug delivery and diagnostics. NanoPump - Low-cost, disposable, biocompatible product for controlled release of large molecules, including therapeutic proteins such as insulin, antibodies and vaccines.

Small molecule drug research and development in the field of central nervous system (CNS) disorders. Circadin™- prolonged-release melatonin.

Immunodiagnostic kits. DipStreak and ChromoStreak for diagnosis of urinary tract infections. NovaStreak for detection of microorganisms in food and dairy products. Uni-Sep for lymphocyte isolation. Extracellular Matrix (ECM) Coated Plastic Ware.

Peptide based active pharmaceutical ingredients for the pharmaceutical industry. Calcium regulators, calcitonin, Parathyroid Hormone. Vasopressin analog Desmopressin. Somatostatin. LHRH analogs Leuprolide, Goserelin, Buserelin, Triptorelin.

Nutraceutical company, specializing in mineral fortifications. Vitamin D fortified instant soluble calcium for improved calcium absorption.

Development of rapid glyco-analytical tests for the food and beverage industries. LactoFact - Lactoferrin Rapid Glyco-Analysis test.

Immunology and hemophilia products. Human surgical sealant used for local hemostasis. Coagulation therapies for hemophilia. Immunoglobulins for prophylaxis of immune disorders. Plasma expanders for treatment of shock, burns and circulatory disorders.

In vitro diagnostic and detection kits for a wide range of analytes including AIDS, chlamydia, hepatitis, rubella, and pregnancy test. ImmunoComb system for solid-phase EIA (enzyme immunoassay).

Development of drug candidates for the treatment of diabetes, rheumatoid arthritis and other autoimmune diseases using hsp60-derived SCAPLs (Small Cyclic Analogs of Protein Loops), which switch off immune system patterns associated with hsp60.

Manufacturer of a wide range of products including cardiovascular and dermatological pharmaceuticals, antibiotics, Ethical topical pharmaceuticals. Formerly Agis.

Bio-pharmaceutical company focused on therapeutics for the central and peripheral nervous systems, and ophthalmologic, cardiovascular and inflammation-related indications. Lipid-based drug delivery systems.

Topical treatment of acute and chronic wounds, diabetic ulcers and other tissue regeneration disorders, using patented microspheres-based technology. Polyheal promotes initiation of granulation, tissue growth and remodeling of damaged skin tissue.

Development of treatments for articular cartilage injuries and other cartilage defects by autologous chondrocyte transplantation.

Drugs that modulate Fibroblast Growth Factor (FGF) system to promote tissue regeneration. FGF formulations for bone fractures, bone loss and spine fusion. FGFR antagonists for short-limbed dwarfism. Autologous cartilage implant BioCart.

U-c fingerprint, a lectin array based platform that enables high throughput, automated analysis of protein glycosylation. Functional Human Protein Arrays with selected sets of human proteins including proteins associated cancer and signal transduction.

Bulk production of E. coli-derived recombinant human cytokines and growth factors as well as monoclonal anti-cytokine and chemokine antibodies.

Proprietary plant cell culture and bioreactor system for efficient, large-scale production of complex human therapeutic proteins, monoclonal antibodies, Glucocerebrosidase enzyme replacement for Gaucher's Disease and other recombinant proteins.

Process development and cGMP manufacturing of recombinant proteins obtained by mammalian cell culture and microbial fermentation. PPS is seeking in-licensing of protein-based products (antibodies, fusion proteins, enzymes) in early development stages.

Wide array of recombinant proteins for life science research: Angiogenic factors, adiponectin, apoliproteins, cytokines, chemokines, growth factors, interleukin, neurotrophins, hormones, enzymes, viral antigens. Human Growth Hormone Binding Protein GHBP.

Ubiquitin-based drugs. HIV drug development program based on RING finger E3 ligases.

Genomics-based drug discovery and development. BiFAR platform for bioinformatics-based target gene selection. Current focus on cancer, fibrotic diseases, ischemic diseases, brain disorders, bone and cartilage disorders, diabetes.

Manufacturer of Over-the-Counter medicines (OTC), generic drugs, antibiotics, etc. Kalgaron for sore throat relief. Fluconazole and lansoprazole. Drugs for diseases of the digestive tract and treatment of pain.

Enzymes for the textile, food, animal feed industries. Products include acid and neutral cellulase, alfa amylase, catalase, lipase, pectinase, protease. Microbial rennet milk clotting enzyme.

Biodegradable hydrogels for local repair of damaged cartilage and bone. Gelrin for restoration of normal joint function by regenerating hyaline cartilage and void filling matrix for bone regeneration designed to be used in osseous injuries.

Rekah develops and markets a wide range of pharmaceuticals, nutraceuticals, vitamins and food additives for human use.

Portable survey meters for alpha, beta and gamma radiation, hydrazine, stable isotopes (O-18), sapphire domes and windows, radioactive products for nuclear medicine, radiopharmaceuticals, labeling services.

Recombinant human growth hormone (GH). Vitamin D derivative for treatment of psoriasis. Recombinant hepatitis B vaccine. Viscoelastic devices for ophthalmology and orthopedics based on hyaluronic acid.

Manufacturer of medical furniture. Over 100 models of hospital beds, stretchers and trolleys, for intensive care, emergency/casualty, maternity, geriatrics, orthopedic, internal, pediatric and home care.

In vitro medical diagnostics testing for sexually transmitted diseases (e.g., Chlamydia), viral diseases, urinary and respiratory infections.

Development of antibody-like polymers, called molecular imprinted polymers (MIPs). Environmental Diagnostic Detection platform for both military and civilian usage, to detect small molecule chemical toxins.

Sintered diamond instruments for dental laboratories designed for grinding, cutting and polishing precious, semi-precious and non-precious metals and Titanium. Instruments for use on porcelain, acrylic and gypsum.

Broadest range of biochemicals, organic chemicals, chromatography products and diagnostic reagents.

Manufacturer of devices for sleep disorder diagnostics. SleepStrip - sleep apnea screener. Respiratory effort sensors, reusable or disposable airflow sensors, motion detection sensors, body position sensors, snoring detection sensors.

Manufacturer of contact lenses, lens solutions and accessories. Multifocal, toric, therapeutic, cosmetic, prosthetic, disposable and gas permeable contact lenses. Colored lenses. Soft K Keratoconus lenses.

Sol-gel nanotechnology for encapsulation of active ingredients in nano size glass (silica) matrices and nanospheres. UV-Pearls safe and inert sunscreen and cosmetics. Acti-Pearls benzoyl peroxide antibacterial acne medication without irritation.

Solumer - Nanotechnology for drug re-engineering and production of water-soluble compounds. Soluble anti-cancer and anti-infective drugs, including Itraconazole, Azithromycin, Clarithomycin, Taxol, etc.

Products for molecular biology research with DNA synthesis facility in Jerusalem to produce custom oligos. Kits for Real-Time PCR, custom probes, siRNA, peptides, antibodies and more.

Microencapsulated vitamins A, E and F suitable for cosmetic formulations providing increased stability of active principles. Microencapsulated natural oils. Stable derivatives of vitamin C.

Pharmaceutical company with a wide range of products, from over-the-counter analgesics and vitamins to injectable anti-cancer drugs.

Distributor of diagnostics and laboratory systems, hygiene and food testing biomedical products in Israel.

Global pharmaceutical company specializing in the development, production and marketing of generic and proprietary branded pharmaceuticals and active pharmaceutical ingredients. Copaxone for the treatment of Relapsing- Remitting Multiple Sclerosis.

Over-the-counter pharmaceuticals. Dermatological preparations, creams and ointments. Non-steroidal anti-inflammatory drug (NSAID) analgesics for rheumatology. Some example products: Acnetrim, Betacorten, Fungimon, Celcox, Diatrim, Dentix.

Autoclaves, and sterilization equipment for the medical, dental, pharmaceutical, bio-technology, and surgical markets. Ultrasonic cleaning systems.

Manufacture of branded generic drugs for cardiovascular medicine, neurology, psychiatry, gastroenterology, and macrolide antibiotics.

Products at pre-clinical stage for prevention of progression of atherosclerosis in patients. Gene therapies targeted to the vascular wall endothelial cells, for both cancer and ischemic disease applications.

Vein Entry Indicator Device (VEID) for intravenous (IV) catheter insertion and spinal punctures. VEID includes a pressure sensor, a signal processor and indicator in a tiny unit that attaches to the end of IV cannula via disposable VEID Adapter.

Novel therapeutics to treat life-threatening infectious diseases based on human monoclonal antibodies (hMAbs) and small molecule drugs. Developing anti-HBV and anti-HCV therapeutics.